Naslov
Antigenic and genomic diversity of central European respiratory syncytial virus strains

Autori
Lukić-Grlić, Amarela ; Cane, P.A. ; Baće, Ana ; Pringle, C.R. ; Mlinarić-Galinović, Gordana ; Popow-Kraupp, Therese

Izvornik
Archives of virology (0304-8608) 143 (1998), 7; 1441-1447

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
respiratory syncytial virus; central Europe; subtypes

Sažetak
Thirty-two RSV strains recovered during the winter months of 1987/88 to 1993/94 from hospitalized children in Vienna, Austria and Zagreb, Croatia were analysed for antigenic and genetic variations. Twenty-nine of the 32 isolates investigated belonged to group A and 3 to group B, with the majority of infections caused by subgroup A1 (21 of 29). Restricion endonuclease mapping of PCR products derived from parts of the N and G gene of 18 group A strains identified 3 distinct lineages, very similar to those defined by analysis of recurrent epidemics in Birmingham, United Kingdom during the same period. Results of this study povide further information on the global pattern of RSV and show that very similar viruses are present simultaneously in widely separated areas.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA