Naslov
SOD-like activity in asthenozoospermia: in vitro inhibition by zinc

Autori
Gavella, Mirjana ; Lipovac, Vaskresenija ; Vučić, Marijana

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Superoxide dismutases: Recent Advances and Clinical Applications / Edeas, Marvin A. - Pariz : MEL-Paris, 1999, 104-104

Skup
International Conference on Superoxide Dismutases : Recent Advances and Clinical Application

Mjesto i datum
Pariz, Francuska, 14.05.1998. - 15.05.1998

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
superoxide dismutase; asthenozoospermia; zinc

Sažetak
The activity of superoxide dismutase is not fully elucidated in asthenozoospermia, characterised by normal spermatozoa concewntration buth with reduced motility. The aim of thisştudy was to evaluate the SOD-like activity as well as in vitro effect of zinc on its activity in astheno and normozoospermia. SOD activity was measured using RanSod test. In vitro effect of zinc was assessed on unfractionated spermatozoa (18). The incubation of sperm suspension with increasing Zn concentration (0.1-3 mM/l) resulted in concentration-dependent decrease in SOD-like activity. The inhibitory effect of zinc was less pronounced in asthenozoospermic than in normozoospermic samples. Results from this study indicate that asthenozoospermia is associated with both an increasaed sperm SOD-like activity and its stronger resistance to the inhibitory effect of z8inc, which might be relevant to the sperm function.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA