Pregled bibliografske jedinice broj: 280607
Thrombotic microangiopathy associated with alpha-interferon therapy for chronic myeloid leukaemia
Thrombotic microangiopathy associated with alpha-interferon therapy for chronic myeloid leukaemia // Nephrology, 11 (2006), 1; 49-52 doi:10.1111/j.1440-1797.2006.00524.x (recenziran, članak, stručni)
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Naslov
Thrombotic microangiopathy associated with alpha-interferon therapy for chronic myeloid leukaemia
Autori
Galešić, Krešimir ; Božić, Borka ; Račić, Ivana ; Sčukanec-Špoljar, Mira
Izvornik
Nephrology (1320-5358) 11
(2006), 1;
49-52
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni
Ključne riječi
chronic myeloid leukaemia; interferon; nephrotic syndrome; renal failure; thrombotic microangiopathy
Sažetak
The association of interferon(IFN)therapy with haemolytic uraemic syndrome in patients with chronic myeloid leukaemia(CML)has been reported infrequently.The pathogenesis of the renal lesion in such cases remains unclear.We report the case of a patient with CML who developed nephrotic syndrome and renal failure while being treated with hydroxyurea and IFN-alpha.Renal biopsy showed features of chronic thrombotic microangiopathy.The discontinuation of IFN-alpha, and a prompt institution of plasmapheresis and steroids resulted in improvement of the nephrotic syndrome and renal function.These findings suggest that longterm IFN-alpha therapy can induce thrombotic microangiopathy and haemolytic uraemic syndrome in patients with CML.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
POVEZANOST RADA
Projekti:
0108254
Ustanove:
Medicinski fakultet, Zagreb,
Klinička bolnica "Dubrava",
Klinički bolnički centar Rijeka
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
Uključenost u ostale bibliografske baze podataka::
- EMBASE (Excerpta Medica)
- MEDLINE