Naslov
Peripartum alterations of maternal and neonatal leukocytes

Autori
Juretić, Emilija

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Proceedings of the 7th World Congress of Perinatal Medicine / Kurjak, Asim ; Chervenak, Frank A - Bolonja : Monduzzi Editore, 2005

ISBN
88-7587-179-5

Skup
7th World Congress of Perinatal Medicine

Mjesto i datum
Zagreb, Hrvatska, 16.09.2005. - 19.09.2005

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
lymphocyte immunophenotype; newborns; parturient women; vaginal delivery

Sažetak
The aim of this study was to identify the influence of labor on maternal and neonatal lymphocyte subpopulations. Peripheral blood was taken from 20 healthy women at vaginal delivery and 3 days later concomitantly with cord and peripheral blood from their newborns. Lymphocyte immunophenotyping was done by 3-color flow-cytometry. All lymphocyte subsets, except for the cytotoxic T cells and cytotoxic T cells with NK activity, were higher in their absolute counts in umbilical blood, but three days later only the levels of T helper and B lymphocytes were higher in newborns than in parturients . There was an expected predominance of naive phenotype in newborns. However, the absolute count of CD4+CD45RO+ cells was as high in umbilical blood as in peripheral blood of parturients at delivery. Of maternal CD8+ cells, an especially high proportion of CD45RA+ and CD45RA+RO+ was found during labor, and three days later the absolute numbers of maternal and neonatal naive CD8+ cells were equal.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA