Naslov
Small particle disease

Autori
Smoljanović, Tomislav ; Bergovec, Marko ; Kolundžić, Robert

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
5th Zagreb International Medical Summit (ZIM) : Abstract Book / Rako, Duje - Zagreb : European Maritime Safety Agency (EMSA), 2005, 23-23

Skup
Zagreb International Medical Summit (5 ; 2005)

Mjesto i datum
Zagreb, Hrvatska, 10.11.2005. - 14.11.2005

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
aseptic loosening ; particle disease ; total hip endoprosthesis

Sažetak
The aim of the study is to present patients, to who uncemented conic, polyethylene acetabular components of total hip endoprosthesis (EP) Endler model, were implanted. The study tries to establish whether the cause of aseptic loosening of polyethylene acetabular components is the particle disease itself, as a reaction on polyethylene, or the causes may be found in other factors as well. In the period from 1985 to 1991, 100 patients (59 females and 41 males) were operated and 110 EP were implanted. The patients were followed from 10 to 16 years (median time 12.47 years). In this study 72 patients with 80-implanted EP were evaluated (radiological, clinical and subjective evaluation). In 42 (52.50%) implanted Endler acetabular components subjective, radiological and clinical findings were very good or excellent. In 38 (47.40%) implanted acetabular components reacetabuloplasty was performed due to aseptic loosening ; in 22 of those components follow-up was 10 years and other 16 had follow-up of 11 to 16 years after the primary implantation. The results confirmed that aseptic loosening developed in one group of the patients (38 EP), but did not develop in the other group (42 EP) after long period. The comparison of postoperative biomechanics conditions which has not shown any statistically significant differences, led to conclusion that beside the main role of polyethylene and mechanic factors, immunological cell reaction and genetics can have an especially significant role. Necessities for new immunological and molecular studies in the application of total hip arthroplasty were stressed out by our results.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

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