Naslov
Trabecular bone volume and bone mineral density correlation in lumbar spine

Autori
Cvijanović, Olga ; Crnčević-Orlić, Željka ; Kristofić, Ines ; Španjol, Josip ; Zoričić, Sanja ; Marić, Ivana ; Bobinac, Dragica

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Bone / Baron, Roland - New York (NY) : Elsevier, 2001, S173-S173

Skup
1st Joint Meeting of the International Bone and Mineral Society and the European Calcified Tissue Society

Mjesto i datum
Madrid, Španjolska, 05.06.2001. - 10.06.2001

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
trabecular bone; lumbar spine; histomorphometric parameters; gender

Sažetak
The objective was to determine correlation between trabecular bone volume (BV/TV) and bone mineral density/content (BMD, BMC) in third lumbar vertebrae (L3) obtained from 45 normal autopsy cases aged from 40 to 80 years (23 females and 22 males) divided in 4 separate age and sex related groups (ranged 40-60 and 60-80 yrs). Vertebrae were analyzed by dual-energy X-ray absorptiometry (DEXA) and histomorphometry. For the histomorphometric analysis vertical trabecular bone cylinders 7 mm thick obtained by drilling the central part of the vertebra were fixed in PFA, embedded undecalcified in MMA, cut into 7 micrometer thick sections, and stained with Goldner trichrome. Estimates of trabecular bone volume (BV/TV) were assessed by using an image analyzed (VAMS, Issa, Zagreb). BMD and BMC measurements in different age and sex-related groups were compared with BV/TV values measured in the same groups. Our results revealed that BMD and BV/TV correlation was strong in a group of women aged from 60 to 80 years (r = 0.9, p<0.05) and in the same age group of men (r = 0, 99, p<0.05). BMC and BV/TV correlation in above mentioned groups was (r = 0.92, p<0, 05) and (r = 0.01, p<0.05), respectively. In a both groups of younger women and men a high correlation between BMD and BV/TV was determined (r = 0.99, p<0.05) and (r = 0.86, p<0.05), respectively. In the same groups BMC and BV/TV correlated poorly (r = 0.42, p<0.05) and (r = 0, 54, p<0.05), respectively. Moreover, BMD and BMC were found significantly higher in younger men and women when compared to elderly (p<0.001). In conclusion, there is a strong correlation between bone mineral density / content and trabecular bone volume, predominantly in elderly of men and women.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

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