Naslov
BPC in liver lesions

Autori
Sikirić, Predrag ; Petek, Marijan ; Ručman, Rudolf ; Seiwerth, Sven ; Grabarević, Željko ; Rotkvić, Ivo ; Jagić, Vjekoslav ; Danilović, Žarko ; Dodig, Milan ; Artuković, Branka ; Đačić, Sanja ; Senečić, Irena ; Giljanović, Sanja ; Banić, Marko ; Brkić, Tomislav ; Komerički, Ljiljana ; Lang, Nada ; Drahotusky, T ; Ćosić, N.

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstracts of the 2nd Symposium on Experimental Ulcer Disease / Experimental Clinical Gastroenterology Vol. 1 1991 / - , 1991, 20-21

Skup
2nd Symposium on Experimental Ulcer Disease

Mjesto i datum
Zagreb, Hrvatska; Otočec, Slovenija, 19.11.1990. - 23.11.1990

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
BPC; lLver lesions; wWistar rats
(BPC; lLver lesions; wistar rats)

Sažetak
A novel substance, colled Body Protection Compound (BPC) was testedagainst different models of hepatic lesions. Different standard models Were used: ligation of bile duct and hepatic artery, restraint stress, and carbon tetrachloride (CCl4)poisoning.BPC has a prounonced beneficial effect on a variety of experimentally induced liver lesions in rats. Relative to liver protection achieved by dopamine agonists the new substance BPC shows even better effectiveness. One of the possible mechanisms of action for BPC could be that of natural scavenger. This is supported by its protective effect in CCL4 poisoning effected in much lower doses than that of conventional scavengers (e.g.vit. E)(micrograms of BPC vs. mg of vit. E)

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti, Veterinarska medicina

POVEZANOST RADA