Pregled bibliografske jedinice broj: 255308
Base protecting groups and synthons for oligonucleotide synthesis
Base protecting groups and synthons for oligonucleotide synthesis
(2003)
CROSBI ID: 255308 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Base protecting groups and synthons for oligonucleotide synthesis
Autori
Iyer, Radhakrishnan P. ; Devlin, Theresa ; Habuš, Ivan ; Yu, Dong ; Agrawal, Sudhir ; Ho, Nan-Hui
Broj patenta
US 6, 531, 589
Godina
2003
Datum patenta
11.03.2003.
Nositelj prava
Hybridon, Inc., Cambridge, MA, US
Sažetak
The invention provides new methods for synthesizing oligonucleotides that allow for deprotection of the oligonucleotides under more mild conditions than existing methods. The invention further provides a nucleoside base protecting group that is stable under oligonucleotide synthesis conditions, but which can be removed under more mild conditions than existing protecting groups, as well as nucleoside synthons having such base protecting groups.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
