Pregled bibliografske jedinice broj: 255186
Di-, tri-, and tetrameric building blocks with carbamate internucleoside linkages for oligonucleotides synthesis
Di-, tri-, and tetrameric building blocks with carbamate internucleoside linkages for oligonucleotides synthesis // Abstracts of Papers 206th ACS National Meeting
Chicago (IL): American Chemical Society (ACS), 1993. (poster, nije recenziran, sažetak, znanstveni)
CROSBI ID: 255186 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Di-, tri-, and tetrameric building blocks with carbamate internucleoside linkages for oligonucleotides synthesis
Autori
Habuš, Ivan ; Agrawal, Sudhir
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
Abstracts of Papers 206th ACS National Meeting
/ - Chicago (IL) : American Chemical Society (ACS), 1993
Skup
206th ACS National Meeting
Mjesto i datum
Chicago (IL), Sjedinjene Američke Države, 22.08.1993. - 27.08.1993
Vrsta sudjelovanja
Poster
Vrsta recenzije
Nije recenziran
Ključne riječi
carbamate internucleoside linkages
Sažetak
Synthesis of di-, tri-, and tetrameric building blocks with carbamate internucleoside linkages was achieved by reaction of mono-, di- or trimeric nucleoside 5^'-O-p-nitrophenyl carbonate intermediates with 3^'-amino-3^'-deoxythymidine. These building blocks were suitably protected at 5^'-position and converted into phosphoramidites, or attached onto CPG, and then used for the chimeric oligonucleotides synthesis. These chimeric oligonucleotides have been studied for their binding properties to complementary nucleic acids and for their nuclease sensitivity.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
