Pregled bibliografske jedinice broj: 254982
Synthesis, Hybridization Properties, Nuclease Stability, and Cellular Uptake of the Oligonucleotide-Amino-beta-Cyclodextrins and Adamantane Conjugates
Synthesis, Hybridization Properties, Nuclease Stability, and Cellular Uptake of the Oligonucleotide-Amino-beta-Cyclodextrins and Adamantane Conjugates // Book of Abstracts, 211th American Chemical Society National Meeting
New Orleans (LA): American Chemical Society (ACS), 1996. (poster, nije recenziran, sažetak, znanstveni)
CROSBI ID: 254982 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Synthesis, Hybridization Properties, Nuclease Stability, and Cellular Uptake of the Oligonucleotide-Amino-beta-Cyclodextrins and Adamantane Conjugates
Autori
Habuš, Ivan ; Zhao, Q. ; Agrawal, Sudhir
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
Book of Abstracts, 211th American Chemical Society National Meeting
/ - New Orleans (LA) : American Chemical Society (ACS), 1996
Skup
Americal Chemical Society National Meeting
Mjesto i datum
New Orleans (LA), Sjedinjene Američke Države, 24.03.1996. - 28.03.1996
Vrsta sudjelovanja
Poster
Vrsta recenzije
Nije recenziran
Ključne riječi
Oligonucleotide; amino-beta-cyclodextrins
Sažetak
Synthesis of the oligonucleotides conjugated with amino derivatives of beta-cyclodextrinand adamantane, at the 3'-end of host oligonucleotide, has been described. The oligonucleotide conjugates were examined for their nuclease stability, hybridization properties, and cellular uptake. Cellular uptake of oligonucleotide-adamantane conjugates in association with 2-(hydroxypropyl)-beta-cyclodextrin as a "carrier" was significantly higher than that of control oligonucleoties.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
