Pregled bibliografske jedinice broj: 254702
Efficient and practical asymmetric synthesis of the taxol C-13 side chain, N-benzoyl-(2R, 3S)-3-phenylisoserine, and its analogs via chiral 3-hydroxy-4-aryl-beta-lactams through chiral ester enolate-imine cyclocondensation
Efficient and practical asymmetric synthesis of the taxol C-13 side chain, N-benzoyl-(2R, 3S)-3-phenylisoserine, and its analogs via chiral 3-hydroxy-4-aryl-beta-lactams through chiral ester enolate-imine cyclocondensation // Journal of organic chemistry, 56 (1991), 5; 1681-1683 doi:10.1021/jo00005a003 (međunarodna recenzija, članak, znanstveni)
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Naslov
Efficient and practical asymmetric synthesis of the taxol C-13 side chain, N-benzoyl-(2R, 3S)-3-phenylisoserine, and its analogs via chiral 3-hydroxy-4-aryl-beta-lactams through chiral ester enolate-imine cyclocondensation
Autori
Ojima, Iwao ; Habuš, Ivan ; Zhao, Mangzhu ; Georg, Gunda I. ; Jayasinghe, Lalith R
Izvornik
Journal of organic chemistry (1520-6904) 56
(1991), 5;
1681-1683
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
taxol ; chiral ester ; enolate-imine
Sažetak
A highly efficient chiral ester enolate-imine condensation giving 3-hydroxy-4-aryl-beta-lactams with >96% ee is successfully applied to the asymmetric synthesis of the enentiomerically pure taxol C-13 side chain, N-benzoyl-(2R, 3S)-3-phenylisoserine, and its analogues.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
Citiraj ovu publikaciju:
Časopis indeksira:
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
