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Pregled bibliografske jedinice broj: 254606

Improved synthesis of oligonucleoside methylphosphonate analogs


Habuš, Ivan; Devlin, Theresa; Iyer, Radhakrishnan P.; Agrawal, Sudhir
Improved synthesis of oligonucleoside methylphosphonate analogs // Bioorganic & Medicinal Chemistry Letters, 6 (1996), 1393-1398 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 254606 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Improved synthesis of oligonucleoside methylphosphonate analogs

Autori
Habuš, Ivan ; Devlin, Theresa ; Iyer, Radhakrishnan P. ; Agrawal, Sudhir

Izvornik
Bioorganic & Medicinal Chemistry Letters (0960-894X) 6 (1996); 1393-1398

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
oligonucleoside methylphosphonates; methylphosphonothioates

Sažetak
Solid-phase synthesis using pent-4-enoyl nucleoside PNT phosphonamidites allow for the facile preparation of oligonucleoside methylphosphonates, methylphosphonothioates and their chimeric analogs. With PNT phosphonamidites, nucleobase and phosphate deprotection, as well as, cleavage from the support can all be accomplished by treatment of the support-bound oligonucleotide with NH4OH (28%, rt, 1 h).

Izvorni jezik
Engleski

Znanstvena područja
Arhitektura i urbanizam, Farmacija



POVEZANOST RADA


Ustanove:
Institut "Ruđer Bošković", Zagreb

Profili:

Avatar Url Ivan Habuš (autor)


Citiraj ovu publikaciju:

Habuš, Ivan; Devlin, Theresa; Iyer, Radhakrishnan P.; Agrawal, Sudhir
Improved synthesis of oligonucleoside methylphosphonate analogs // Bioorganic & Medicinal Chemistry Letters, 6 (1996), 1393-1398 (međunarodna recenzija, članak, znanstveni)
Habuš, I., Devlin, T., Iyer, R. & Agrawal, S. (1996) Improved synthesis of oligonucleoside methylphosphonate analogs. Bioorganic & Medicinal Chemistry Letters, 6, 1393-1398.
@article{article, author = {Habu\v{s}, Ivan and Devlin, Theresa and Iyer, Radhakrishnan P. and Agrawal, Sudhir}, year = {1996}, pages = {1393-1398}, keywords = {oligonucleoside methylphosphonates, methylphosphonothioates}, journal = {Bioorganic and Medicinal Chemistry Letters}, volume = {6}, issn = {0960-894X}, title = {Improved synthesis of oligonucleoside methylphosphonate analogs}, keyword = {oligonucleoside methylphosphonates, methylphosphonothioates} }
@article{article, author = {Habu\v{s}, Ivan and Devlin, Theresa and Iyer, Radhakrishnan P. and Agrawal, Sudhir}, year = {1996}, pages = {1393-1398}, keywords = {oligonucleoside methylphosphonates, methylphosphonothioates}, journal = {Bioorganic and Medicinal Chemistry Letters}, volume = {6}, issn = {0960-894X}, title = {Improved synthesis of oligonucleoside methylphosphonate analogs}, keyword = {oligonucleoside methylphosphonates, methylphosphonothioates} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus





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