Pregled bibliografske jedinice broj: 249688
Comparison of immunogenicity of recombinant and plasma derived hepatitis B antigen in guinea pigs
Comparison of immunogenicity of recombinant and plasma derived hepatitis B antigen in guinea pigs // Vaccine, 8 (1990), 585-589 doi:10.1016/0264-410X(90)90014-D (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 249688 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Comparison of immunogenicity of recombinant and
plasma derived hepatitis B antigen in guinea pigs
Autori
Valinger, Zdenka ; Treščec, Anđa ; Tomašić, Jelka
Izvornik
Vaccine (0264-410X) 8
(1990);
585-589
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
HBsAg ; immunoassay ; guinea pig ; plasma-derived ; recombinant
Sažetak
Four different preparations of hepatitis B antigen (HBsAg) were tested in parallel with respect to their ability to elicit anti-HBs in guinea pigs. We compared the effect of low doses od human plasma derived and recombinant HBsAg in purified forms or prepared as vaccines, respectively. The highest titre of anti-HBs developed was detected in guinea pigs immunized with plasma derived HBsAg, followed by the response in animals immunized with plasma derived vaccine. Purified recombinant antigen and recombinant vaccine exhibited poor immunogenicity compared with plasma derived antigen preparations.
Izvorni jezik
Engleski
Znanstvena područja
Kemija, Temeljne medicinske znanosti, Biotehnologija
Citiraj ovu publikaciju:
Časopis indeksira:
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
