Naslov
Kinetics of the Solvolyses of Benzhydryl Derivatives: Basis for the Construction of a Comprehensive Nucleofugality Scale

Autori
Denegri, Bernard ; Andre, Streiter ; Ofial, Armin ; Jurić, Sandra ; Kronja, Olga ; Mayr, Herbert

Izvornik
Chemistry : a European journal (0947-6539) 12 (2006), 6; 1648-1656

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
carbocations • kinetics • nucleophilic substitution • reaction mechanisms • solvent effects

Sažetak
A series of 21 benzhydrylium ions (diarylmethylium ions) are proposed as reference electrofuges for the development of a general nucleofugality scale, where nucleofugality refers to a combination of leaving group and solvent. A total of 167 solvolysis rate constants of benzhydrylium tosylates, bromides, chlorides, trifluoroacetates, 3, 5-dinitrobenzoates, and 4-nitrobenzoates, two-thirds of which have been determined during this work, were subjected to a least-squares fit according to the correlation equation log k25 °C = sf(Nf + Ef), where sf and Nf are nucleofuge-specific parameters and Ef is an electrofuge-specific parameter. Although nucleofuges and electrofuges characterized in this way cover more than 12 orders of magnitude, a single set of the parameters, namely sf, Nf, and Ef, is sufficient to calculate the solvolysis rate constants at 25 °C with an accuracy of ± ; ; 16 %. Because sf1 for all nucleofuges, that is, leaving group/solvent combinations, studied so far, qualitative discussions of nucleofugality can be based on Nf.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

Napomena
Ispravak u: 12 (2006) (21) str.5415.

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