Naslov
Posttransplant Renal Rejection: Comparison of Quantitative Scintigraphy, US and MR Imaging
(Posttransplant Renal Rejection:Comparison of Quantitative Scintigraphy, US and MR Imaging)

Autori
Hricak, Hedvig ; Terrier , Francois ; Marotti, Miljenko ; Engelstad, Barry L: Filly, Roy A ; Vincenti, Flavio ; Duca, Robert M ; Bretan, Peter N ; Higgins, Charles B ;

Izvornik
Radiology (0033-8419) 162 (1987); 683-688

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
kidney ; MR studies ; radionuclide study ; ultrasound ; US ; comparative studies

Sažetak
Accuracy of ultrasonography (US), quantitative scintigraphy, and magnetic resonance (MR) imaging in diagnosis of acute renal allograft rejection was studied in 46 patients who underwent renal biopsy. Thirty-three patients had acute rejection ; six, cyclosporine nephrotoxicity, as shown by biopsy, clinical findings, and follow-up study ; two, acute tubular necrosis ; and five, normal biopsy findings and renal function. Accuracy in demonstrating rejection was 72% for US and 73 for scintigraphy, indicating no signifincant difference between the two. MR imaging imaging was significantly more accurate, reaching a level of 98%. Howeever, accuracy of MR in demonstrating acute tubular necrosis in a larger number of patients is not known, and its accuracy in indicating recurrent glomerulopathy or infectious disease has not been adressed. The definitive role of MR in evaluating posttransplant renal failure is currently not established, but because of its high sensitivity in detecting renal abnormality, MR can used for cases when results of US or scintigraphy are equivocal or contradict clinical impressions or then biopsy cannot be performed for medical reasons.

Izvorni jezik
Engleski

POVEZANOST RADA