Naslov
Imunocompetence in patients with malignant tumors of the head and neck

Autori
Stošić, Aleksandar ; Manestar, Darko ; Kovačević, Miljenko ; Žuža, Branko ; Dorić, Miljenko ; Rukavina, Daniel

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni

Izvornik
Abstracts of the First Congress of the Yugoslavian Immunology Society ; u: Periodicum Biologorum (1986)(S) / - , 1986, 548-549

Skup
Congress of the Yugoslavian Immunology Society (1 ; 1985)

Mjesto i datum
Opatija, Hrvatska, 21.10.1985. - 25.10.1985

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Domaća recenzija

Ključne riječi
malignant tumors; immune response; mitogens

Sažetak
Controversial data can be found in literature concerning the role of immunological mechanisms in the growth and spread of cancer. The purpose of the present investigation was to determine whether changes exist in immune responsiveness in patients with malignant tumors of the head and neck. The immune reactivity was assessed by the ability of peripheral blood lymphocytes to respond to Phytohemagglutinin (PHA), Concanavalin A (Con-A) and Pokeweed mitogen (PWM). The responses to all three mitogens were significantly lower in patients with recurrent tumors in comparison to stage I and II. The results presented indicate a decrease of immunological function in cancer patients.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA