Pregled bibliografske jedinice broj: 237109
Probabilistic kinetic model of slow oxidation of low-density lipoprotein III. Hydroperoxide-free initiation
Probabilistic kinetic model of slow oxidation of low-density lipoprotein III. Hydroperoxide-free initiation // Journal for Chemical Information and Modeling, 45 (2005), 6; 1616-1620 (međunarodna recenzija, članak, znanstveni)
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Naslov
Probabilistic kinetic model of slow oxidation of low-density lipoprotein III. Hydroperoxide-free initiation
Autori
Krilov, Dubravka ; Herak, Janko N.
Izvornik
Journal for Chemical Information and Modeling (0095-2338) 45
(2005), 6;
1616-1620
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
atherosclerosis; LDL; oxidation; seeded hydroperoxides; tocopherol-mediated peroxidation
Sažetak
Theoretical model is presented that explains slow copper-induced oxidation of low-density lipoprotein in the systems free of seeded hydroperoxydes. The model is based on the probabilistic kinetic theory, modified to take into account different radical generation rates by oxidized and reduced forms of the metal ions. It is shown that the initiation and progression of the LDL oxidation can take place in any LDL dispersion by metal-induced oxidation of  -tocopherol, one of the constituents of LDL, and formation of slowly reacting  -tocopheroxyl radical. Selected values of several adjustable parameters define actual temporal profiles of the quantities defining the oxidation process
Izvorni jezik
Engleski
Znanstvena područja
Fizika, Kemija, Biologija
POVEZANOST RADA
Projekti:
0006421
Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb,
Medicinski fakultet, Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- SCI-EXP, SSCI i/ili A&HCI
Uključenost u ostale bibliografske baze podataka::
- CA Search (Chemical Abstracts)
