Naslov
Sotalol and non sustained ventricular tachycardia in hypertrophic cardiomyopathy - Case report

Autori
Sokol, Ivan ; Kirin, Marijan ; Vincelj, Josip ; Putarek, Krešimir ; Bergovec, Mijo ; Soldo, Dragica ; Božikov, Velimir.

Izvornik
Cardiovascular Drugs and Therapy (0920-3206) 11 (1997), Supplement 2;

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, kongresno priopcenje, stručni

Ključne riječi
sotalol; ventricular tachycardia; hypertrophic cardiomyopathy

Sažetak
We report a 57 year-old man with nonobstructive hypertrophic cardiomyopathy (HCM) previously continuosly treated with beta-blockers last ten years, presented with monomorphic and polymorphic runs of NS-VT associated with oscillatory arterial hypertension and symptomatic deterioration. ECG demonstrated abnormal Q-wave in leads II, III, aVF and V4-6 simulating inferolateral infarction with multifocal premature ventricular contractions (PVC) occuring as a single contraction and a complets. Holter recorded frequent multifocal PVCs up to 30 per hour occuring as a single contractions, couplets or repetitive forms mostly salvos or NS-VT. Echocardiography and chest roentgenography showed characteristic morphology of nonobstructive HCM. He was treated unsuccessfully with class I agents disopyramide, mexiletine, propafenone and class III agent amiodarone. In our case, the treatment with low dose d, l-sotalol up to 320 mg, completely controlled NS-VT with decrease in the severity of clinical symptoms. ECG and Holter recording obtained at final assessment two months after the treatment with d, l-sotalol was started, revealed no significant drug-related changes in PR, QRS-duration, ST-segment and rate-corrected Q-T interval. In this report it was intention to show good effect of d, l-sotalol in suppression NS-VT in patients with nonobstructive HCM particularly in comparison with other used antiarrhythmics.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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