Pregled bibliografske jedinice broj: 223322
Atrazine exposure decreases cell proliferation in Chinese Hamster Ovary (CHO-K1) cell line
Atrazine exposure decreases cell proliferation in Chinese Hamster Ovary (CHO-K1) cell line // Bulletin of Environmental Contamination and Toxicology, 81 (2008), 2; 205-209 doi:10.1007/s00128-008-9425-6 (međunarodna recenzija, članak, znanstveni)
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Naslov
Atrazine exposure decreases cell proliferation in Chinese Hamster Ovary (CHO-K1) cell line
Autori
Kmetič, Ivana ; Gaurina Srček, Višnja ; Slivac, Igor ; Šimić, Branimir ; Kniewald, Zlatko ; Kniewald, Jasna
Izvornik
Bulletin of Environmental Contamination and Toxicology (0007-4861) 81
(2008), 2;
205-209
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
atrazine; CHO-K1 cells; IC50 values; apoptosis
Sažetak
The aim of this study was to determine the toxic effect of atrazine at the ovarian cellular level. Chinese Hamster Ovary (CHO-K1) cell line was used to evaluate the degree of in vitro atrazine cytotoxicity and the morphological changes were followed during the cell death. Application of four bioassays confirmed that atrazine decreases ovarian cell proliferation and IC50 were determined with each assay after 72 h of exposure. The level of apoptosis in atrazine treated cells was low.
Izvorni jezik
Engleski
Znanstvena područja
Biotehnologija
POVEZANOST RADA
Projekti:
058-0582184-2232 - Endokrino-aktivne supstancije u hrani i oštećenja reproduktivnog sustava (Šimić, Branimir, MZOS ) ( CroRIS)
058-0582184-2414 - Nekliničke metode ispitivanja tvari iz okoliša na stanicama sisavaca i riba (Gaurina-Srček, Višnja, MZOS ) ( CroRIS)
Ustanove:
Prehrambeno-biotehnološki fakultet, Zagreb
Profili:
Branimir Šimić
(autor)
Zlatko Kniewald
(autor)
Ivana Kmetič
(autor)
Višnja Gaurina-Srček
(autor)
Igor Slivac
(autor)
Jasna Kniewald
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE