Pregled bibliografske jedinice broj: 218243
Laboratory standards in diagnosis and therapy monitoring of rheumatoid arthritis
Laboratory standards in diagnosis and therapy monitoring of rheumatoid arthritis // New trends in classification, monitoring and management of autoimmune diseases
Zagreb: Medicinska naklada, 2005. str. 31-38 (pozvano predavanje, međunarodna recenzija, cjeloviti rad (in extenso), znanstveni)
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Naslov
Laboratory standards in diagnosis and therapy
monitoring of rheumatoid arthritis
Autori
Tešija Kuna, Andrea
Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni
Izvornik
New trends in classification, monitoring and management of autoimmune diseases
/ - Zagreb : Medicinska naklada, 2005, 31-38
Skup
The 5th FESCC Continuous Postgraduate Course in Clinical Chemistry: New trends in classification, monitoring and management of autoimmune diseases
Mjesto i datum
Dubrovnik, Hrvatska, 15.10.2005. - 16.10.2005
Vrsta sudjelovanja
Pozvano predavanje
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
laboratory standards ; diagnosis ; rheumatoid arthritis
Sažetak
Rheumatoid arthritis (RA) is the most common inflammatory rheumatic disease with a prevalence of 0.5% to 1% in the general population and a male to female ratio of 2.5:1. The disease usually manifests at the age of 40- 70 years, its incidence rising with age. The lowest prevalence of RA is reported from rural Africa, and highest in particular groups of native Americans (Pima and Chippewa). Mainly, it is an inflammation of the synovial membrane (which lines the joint cavity and secretes synovial fluid acting as a 'lubricant') and hyperplasia of the synovial tissue with considerable infiltration of lymphocytes, macrophages and plasma cells. Typical clinical symptoms of RA include symmetrical synovitis, which initially involves only one pair of small finger joints (proximal interphalangeal, metacarpophalangeal or metatarsophalangeal joints) with painful episodes and erythema. During the disease characterized by acute inflammatory episodes, destructive changes of the joints develop and result in deformity and progressive functional impairment. RA is also a systemic inflammatory disorder with extra- articular manifestations such as rheumatoid nodes in subcutaneous tissues, pleuritis, pericarditis, ulcerations, and digital gangrene due to immune complex deposits...
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
POVEZANOST RADA