Pregled bibliografske jedinice broj: 21651
Influence of immunomodulator conjugated to polysaccharide antigenson humoral immune response
Influence of immunomodulator conjugated to polysaccharide antigenson humoral immune response // Abstracts, John Humphrey Course "Effector Functions of Immune Cells"
Dubrovnik, Hrvatska, 1998. (poster, međunarodna recenzija, sažetak, znanstveni)
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Naslov
Influence of immunomodulator conjugated to polysaccharide antigenson humoral immune response
Autori
Špoljar, Beata ; Glaudemans, Cornelis, P.J. ; Tomašić, Jelka
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
Abstracts, John Humphrey Course "Effector Functions of Immune Cells"
/ - , 1998
Skup
John Humphrey Course "Effector Functions of Immune Cells"
Mjesto i datum
Dubrovnik, Hrvatska, 11.10.1998. - 14.10.1998
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
polysaccharides; peptidoglycan monomer
Sažetak
Peptidoglycan monomer (PGM),the disaccharide pentapeptide and the derivative Boc-Tyr-PGM were coupled to two polysccharides: the glucuronoxylomannan (GXM) from Cryptococcus neoformans and to the dextran FP 70. Both polysaccharides were activated by CNBr, coupled to adipic acid hydrazide and reacted with Boc-Tyr-PGM. Mice were immunized with the polysaccharide or conjugates of the polysaccharides and immunomodulators, respectively. Mice sera were analyzed for anti-dextran or anti-GXM content by appropriate ELISA. The tested conjugates exhibited immunostimmulating effect on humoral response.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
