Pregled bibliografske jedinice broj: 212534
Antitumor efficancy of intrahepatic natural killer T cells in animal models
Antitumor efficancy of intrahepatic natural killer T cells in animal models // Medicinski razgledi Suppl 5 (2004), 43 ; 159-165 / Kotnik, Vladimir (ur.).
Ljubljana: Slovensko imunološko društvo, 2004. str. 159-165 (pozvano predavanje, međunarodna recenzija, cjeloviti rad (in extenso), znanstveni)
CROSBI ID: 212534 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Antitumor efficancy of intrahepatic natural killer T cells in animal models
Autori
Radošević-Stašić, Biserka
Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni
Izvornik
Medicinski razgledi Suppl 5 (2004), 43 ; 159-165
/ Kotnik, Vladimir - Ljubljana : Slovensko imunološko društvo, 2004, 159-165
Skup
Tumor Immunology and Immunointerventions 2nd Slovenian immunology Congress with international participation
Mjesto i datum
Portorož, Slovenija, 20.10.2004. - 22.10.2004
Vrsta sudjelovanja
Pozvano predavanje
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
Natural killer T cells; liver; partial hepatectomy; autoimmune diabetes; peptidoglycan monomer
Sažetak
The extrathymic generation of the NKT cells were demonstrated in mice subjected to a) partial hepatectomy (pHx), b) injections of streptozotocin (provoking autoimmune diabetes) and c) injections of peptidoglycan-monomer-PGM and PGM-Zn, prepared from Gram + bacteria. In all models, freshly isolated hepatic and particularly splenic MNLC became markedly cytotoxic to YAC-1 cells, as well as to syngeneic thymocytes, suggesting that autoreactive NKT cells in the liver, might be key players in the regulation of anti-tumor immunity and epithelial cell proliferation.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
POVEZANOST RADA
