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Pregled bibliografske jedinice broj: 201237

Synthesis, characterisation and in vitro antimicrobial activity of novel sulfonylureas of 15-memberded azalides

Bukvić Krajačić, Mirjana; Kujundžić, Nedjeljko; Dumić, Miljenko; Cindrić, Mario; Brajša, Karmen; Metelko, Biserka; Novak, Predrag
Synthesis, characterisation and in vitro antimicrobial activity of novel sulfonylureas of 15-memberded azalides // Journal of antibiotics, 58 (2005), 6; 380-389 doi:10.1038/ja.2005.48 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 201237 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Synthesis, characterisation and in vitro antimicrobial activity of novel sulfonylureas of 15-memberded azalides

Autori
Bukvić Krajačić, Mirjana ; Kujundžić, Nedjeljko ; Dumić, Miljenko ; Cindrić, Mario ; Brajša, Karmen ; Metelko, Biserka ; Novak, Predrag

Izvornik
Journal of antibiotics (0021-8820) 58 (2005), 6; 380-389

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
azalides; sulfonylurea; synthesis; NMR and MS; antimicrobial activity

Sažetak
A series of the novel benzenesulfonylurea derivatives of 15-membered azalides were prepared and their structures elucidated by NMR and IR spectroscopic methods and mass spectrometry. Minimal inhibitory concentration (MIC) of all the compounds were determined on a panel of susceptible and resistant Gram positive and Gram negative bacterial strains. Several compounds with benzenesulfonyl group linked directly to macrocyclic ring had better antibacterial activity against Streptococcus pneumoniae and inducibly resistant Streptococcus pyogenes strain in comparison with azithromycin, while the other molecules did not show improvements in the overall in vitro profile

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA

Projekti:
0006543
0119641

Ustanove:
Pliva-Istraživački institut,
Prirodoslovno-matematički fakultet, Zagreb

Profili:

Avatar Url Mirjana Bukvić (autor)

Avatar Url Miljenko Dumić (autor)

Avatar Url Karmen Brajša (autor)

Avatar Url Mario Cindrić (autor)

Avatar Url Biserka Metelko (autor)

Avatar Url Predrag Novak (autor)

Poveznice na cjeloviti tekst rada:

doi www.nature.com

Citiraj ovu publikaciju:

Bukvić Krajačić, Mirjana; Kujundžić, Nedjeljko; Dumić, Miljenko; Cindrić, Mario; Brajša, Karmen; Metelko, Biserka; Novak, Predrag
Synthesis, characterisation and in vitro antimicrobial activity of novel sulfonylureas of 15-memberded azalides // Journal of antibiotics, 58 (2005), 6; 380-389 doi:10.1038/ja.2005.48 (međunarodna recenzija, članak, znanstveni)
Bukvić Krajačić, M., Kujundžić, N., Dumić, M., Cindrić, M., Brajša, K., Metelko, B. & Novak, P. (2005) Synthesis, characterisation and in vitro antimicrobial activity of novel sulfonylureas of 15-memberded azalides. Journal of antibiotics, 58 (6), 380-389 doi:10.1038/ja.2005.48.
@article{article, author = {Bukvi\'{c} Kraja\v{c}i\'{c}, Mirjana and Kujund\v{z}i\'{c}, Nedjeljko and Dumi\'{c}, Miljenko and Cindri\'{c}, Mario and Braj\v{s}a, Karmen and Metelko, Biserka and Novak, Predrag}, year = {2005}, pages = {380-389}, DOI = {10.1038/ja.2005.48}, keywords = {azalides, sulfonylurea, synthesis, NMR and MS, antimicrobial activity}, journal = {Journal of antibiotics}, doi = {10.1038/ja.2005.48}, volume = {58}, number = {6}, issn = {0021-8820}, title = {Synthesis, characterisation and in vitro antimicrobial activity of novel sulfonylureas of 15-memberded azalides}, keyword = {azalides, sulfonylurea, synthesis, NMR and MS, antimicrobial activity} }
@article{article, author = {Bukvi\'{c} Kraja\v{c}i\'{c}, Mirjana and Kujund\v{z}i\'{c}, Nedjeljko and Dumi\'{c}, Miljenko and Cindri\'{c}, Mario and Braj\v{s}a, Karmen and Metelko, Biserka and Novak, Predrag}, year = {2005}, pages = {380-389}, DOI = {10.1038/ja.2005.48}, keywords = {azalides, sulfonylurea, synthesis, NMR and MS, antimicrobial activity}, journal = {Journal of antibiotics}, doi = {10.1038/ja.2005.48}, volume = {58}, number = {6}, issn = {0021-8820}, title = {Synthesis, characterisation and in vitro antimicrobial activity of novel sulfonylureas of 15-memberded azalides}, keyword = {azalides, sulfonylurea, synthesis, NMR and MS, antimicrobial activity} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE

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