Naslov
Cardiovascular risk factors and diseases strongly predict hemodialysis treatment outcome in maintenance hemodialysis patients

Autori
Rački, Sanjin ; Zaputović, Luka ; Vujičić, Božidar ; Mavrić, Žarko ; Gržetić, Mirjana ; Ravlić-Gulan, Jagoda

Izvornik
Croatian medical journal (0353-9504) 46 (2005), 6; 936-941

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Haemodialysis; Cardiovascular Disease; Treatment; Outcome

Sažetak
Aim. To identify independent predictors of hemodialysis treatment outcome among major cardiovascular risk factors and pre-existent cardiovascular diseases in maintenance hemodialysis patients with the end-stage renal disease. Methods. A total of 144 prevalent patients on maintenance hemodialysis at Rijeka University Hospital between 1998 and 2003 were included in the prospective clinical study. Pre-existent cardiovascular risk factors and diseaseswere identified, as well as their relation to hemodialysis treatment outcome. Primary outcome measurewas death, and secondary outcomemeasure was the length of time from the beginning of patient&#8217; s hemodialysis treatment to the end of follow-up, ie, end of the study or patient&#8217; s death. The independent variables on hemodialysis treatment outcome were identified with the multiple linear regressions. Results. Cardiovascular diseases were themajor cause of death in 40 (60.6%) patients. Acute myocardial infarction in 15 (22.7%) patients was the major single cause of death. Among risk factors, hyperglycemia (P<0.001), low delivered dialysis dose (P<0.001), use of semi-synthetic dialysis membrane (P<0.001), and anemia (P=0.041) were independent predictors of hemodialysis treatment outcome. Hypertensive heart disease (P<0.001), ischemic heart disease (P<0.001), and dilated cardiomyopathy (P=0.016) were independent predictors of the hemodialysis treatment outcome. Conclusions. Cardiovascular diseases were the leading cause of death in hemodialysis patients. There was also high prevalence of cardiovascular risk factors and pre-existent cardiovascular diseases. Several of them were independent predictors of the hemodialysis treatment outcome.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA