Naslov
LDH i CRP kao pojedinačni prediktori težine akutnog pankreatitisa
(LDH and CRP as Single Predictors for Severity in Acute Pancreatitis)

Autori
Milić, Sandra ; Radić, Mladen ; Krznarić Zrnić, Irena ; Fišić, Elizabeta ; Baraba, Kristina ; Štimac, Davor

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Zbornik radova 10.godišnjeg sastanka Hrvatskog gastroenterološkog društva / Rotkvić, Ivo - Zagreb, 2004, 44-45

Skup
10. godišnji sastanak Hrvatskog gastroenterološkog društva

Mjesto i datum
Bizovac, Hrvatska, 04.11.2004. - 06.11.2004

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
LDH; CRP; akutni pankreatitis; prediktivni parametri
(LDH; CRP; acute pancreatitis; predictive parametars)

Sažetak
BACKGROUND AND AIMS: Ranson and Glasgow scores are routinely used for prediction of severity in acute pancreatitis. We undertook a prospective study to investigate a role of LDH and CRP as potential single predictors for severity in acute pancreatitis. PATIENTS AND METHODS: In our study we included 121 patients with diagnosis of acute pancreatitis admitted to our hospital during last two years. The inclusion criteria consisted of combination of clinical features, a typical case history, elevation of serum pancreatic enzymes and diagnosis confirmed by imaging studies (US or CT). We used Ranson score for assesment of severity and compared it with single parameters as LDH and CRP on first and third day after admission. Cut off values for predicting local and systemic complications were &#61619; 3 for Ranson score, 320 IU for LDH and 5 mg/L for CRP. RESULTS: Ranson score has specificity of 65, 67% and sensitivity of 40, 74% in predicting complications, while CRP (62, 77%, 60, 21%) and LDH (60, 87%, 53, 19%) on first and third day have lower specificity and lower sensitivity ( < 40%). CONCLUSIONS: Ranson as a predictor has higher sensitivity and specificity than LDH and CRP as single predictors in prediction of complications in acute pancreatitis. Diagnostic accuracy varies from 49, 59% for LDH and CRP on day one to 54, 55% for LDH on day 3 and Ranson score.

Izvorni jezik
Hrvatski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA