Naslov
Frequency of micronucleated erythrocytes in the rat bone marrow exposed to 2.45 GHz radiation

Autori
Trošić, Ivančica ; Bušljeta, Ivana

Izvornik
Physica scripta (0031-8949) T118 (2005); 168-170

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
2.45 GHz irradiation; rats; polychromatic erythrocytes; micronucleated bone marrow red cells

Sažetak
Wistar rats were exposed to 2.45 GHz continuous, radiofrequency microwave (RF/MW) field 2 hours daily, 7 days weekly, at power density 5-10 mW/cm2. Four subgroups were created in order to be irradiated 4, 16, 30 and 60 hours. Sham-exposed controls were included in the study. Animals were euthanized on final irradiation day of each treated subgroup. Bone marrow smears were examined to determine the extent of genotoxicity after particular treatment time. Mann-Whitney test was used for statistical evaluation of data. In comparison to the sham-exposed subgroups, the findings of polychromatic erythrocytes revealed significant differences for the 8th and 15th experimental day. Bone marrow erythrocyte maturation and/or proliferation initiated by subthermogenic RF/MW irradiation showed temporary disturbance. Thereafter, the frequency of micronucleated bone marrow red cells was significantly increased after 15 irradiation treatments. Comparison of micronucleus frequency data obtained after 2, 8 and 30 irradiation treatments did not reveal statistically significant differences between sham and treated subgroups. Under the applied experimental conditions, RF/MW irradiation initiates transitory cytogenetic effect manifested with micronucleus formation in erythropoietic cells.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

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