Pregled bibliografske jedinice broj: 199698
Mitogenicity of the earthworm's (Eisenia Foetida) insulin-like proteins
Mitogenicity of the earthworm's (Eisenia Foetida) insulin-like proteins // Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 104 (1993), 4; 723-729 doi:10.1016/0305-0491(93)90204-I (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 199698 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Mitogenicity of the earthworm's (Eisenia Foetida) insulin-like proteins
Autori
Hrženjak, Maja ; Kobrehel, Đorđe ; Levanat, Sonja ; Jurin, Mislav ; Hrženjak, Terezija
Izvornik
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology (1096-4959) 104
(1993), 4;
723-729
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
mitogenicity ; insulin-like proteins
Sažetak
Biologically active glycolipoprotein complex (G-90), isolated from whole earthworm tissue extract (Eisenia foetida), was separated into seven fractions by gel-filtration. It has been shown by radioimmunoassay that each of the fractions, except the lightest one, is cross-reactive with porcine anti-insulin antibodies. Molecules that possess such activity were detected by immunoblotting. All fractions, except the heaviest and the lightest one, stimulate mammalian normal and transformed cell proliferation in serum-free conditions in vitro. The intensity of stimulation depends on cell type. Stimulation is completely abolished if the medium is supplemented with fetal calf serum.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
POVEZANOST RADA
Ustanove:
Veterinarski fakultet, Zagreb,
Pliva-Istraživački institut,
Institut "Ruđer Bošković", Zagreb
Profili:
Mislav Jurin
(autor)
Maja Hrženjak
(autor)
Sonja Levanat
(autor)
Đorđe Kobrehel
(autor)
Terezija Hrženjak
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus