Naslov
Modulation of BPC Gastroprotective effect

Autori
Sikirić, Predrag ; Petek, Marijan ; Ručman, Rudolf ; Seiwerth, Sven ; Grabarević, Željko ; Rotkvić, Ivo ; Jagić, Vjekoslav ; Duvnjak, Marko ; Cviko, Aida ; Turković, Branko ; Miše, Stjepan ; Kolega, Marko ; Dodig, Milan ; Sallmani, Ahmet ; Đačić, Sanja ; Mildner, Boris ; Erceg, Damir

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni

Izvornik
The III. International symposium on gastrointestinal cytoprotection / Mozsik, Gy. ; Sikirić, Predrag - Zagreb : Pergamon Press & Mladost, 1991, 269-270

Skup
The III. International symposium on gastrointestinal cytoprotection

Mjesto i datum
Pečuh, Mađarska, 07.10.1991. - 08.10.1991

Vrsta sudjelovanja
Plenarno

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
BPC; gastroprotective effect

Sažetak
To elucidate any mechanism, the observed events should be investigated also by the way of their modulations induced by particular organ ablation. For body protection compound (BPC), a novel partially characterized gastric juice peptide (1), the gastroprotection has been largely studied in normal and modified conditions. Between a huge range of organoprotective effects (intestinium, kidney, liver, pancreas, inflammation, diabetes mellitus), the gastroprotection has been supposed by us (1) to be firstly a crucial pattern in general concept of organoprotection, and secondly for BPC beneficial action, as the mediator of the sugested "stomach-stress organoprotective response". Therefore, the obtained modulations: (1) abolition: ovariectomy, demedullation ; (2) decrease: thyroparathyroidoectomy ; (3) no change: orchidectomy, vagotomy, spleenectomy - could probably be complex as well as specific way of BPC beneficial action. 1. Sikirić, P. et al. Exp. Clin, Gastroenterol. 1: 15-16, 1991.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biologija, Temeljne medicinske znanosti

POVEZANOST RADA