Naslov
Macrolides

Autori
Alihodžić, Suleman ; Berdik, Andrea ; Cardullo, Francesca ; Hutinec, Antun ; Lazarevski, Gorjana ; Lociuro, Sergio ; Marušić-Ištuk, Zorica ; Mutak, Stjepan ; Pozzan, Alfonso ; Đerek, Marko

Broj patenta
WO0232917A1

Godina
2000

Datum patenta
25.04.2002.

Nositelj prava
PLIVA - Research Institute Ltd. i GlaxoSmithKline (GSK), Zagreb, Hrvatska

Sažetak
The present invention relates to a compound of formula (I) wherein R1 is hydrogen or together with R2 is oxo ; R2 represents hydroxy, OC(O)XR7, OC(O)NHXR7 or R2 together with R1 is an oxo group ; R3 is hydrogen or a hydroxyl protecting group ; R4 is hydrogen or XR7 ; R5 is hydrogen, XR7 or C(O)NHXR7 ; R6 is hydrogen or R5 and R6 taken together with the intervening atoms form a cyclic carbonate having the following structure and pharmaceutically acceptable salts and solvates thereof and solvates thereof ; to processes for their preparation and their use in the therapy or prophylaxis of systemic or topical bacterial infections in a human or animal body.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

POVEZANOST RADA