Pregled bibliografske jedinice broj: 194387
Evidence of an acute phase response in dogs naturally infected with Babesia canis
Evidence of an acute phase response in dogs naturally infected with Babesia canis // Veterinary Parasitology, 144 (2007), 3-4; 242-250 doi:10.1016/j.vetpar.2006.10.004 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 194387 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Evidence of an acute phase response in dogs naturally infected with Babesia canis
Autori
Matijatko, Vesna ; Mrljak, Vladimir ; Kiš, Ivana ; Kučer, Nada ; Foršek, Jadranka ; Živičnjak, Tatjana ; Romić, Željko ; Šimec, Zoran ; Ceron, Joaquin Jose
Izvornik
Veterinary Parasitology (0304-4017) 144
(2007), 3-4;
242-250
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
babesiosis; dog; acute phase reaction; C-reactive protein; serum amyloid A; haptoglobin
Sažetak
The erythrocyte sedimentation rate (ESR), white blood cell count (WBC), haematocrit (HCT) and platelet number (PLT) were quantified and compared with the acute phase proteins (APPs) in dogs naturally infected with Babesia canis and healthy dogs. Both groups were treated with imidocarb dipropionate on the day of admission and both groups were monitored for all parameters on the admission day and on the first, second, third, fourth and seventh days in order to determine the presence of an acute phase reaction, to assess the diagnostic value of these markers in uncomplicated canine babesiosis and to evaluate the use of APPs in treatment monitoring. It was demonstrated that an acute phase response occurs in dogs naturally infected with Babesia canis, with significant increases in the concentration of major acute phase proteins. The serum concentration of C-reactive protein (CRP), serum amyloid A (SAA) and the erythrocyte sedimentation rate (ESR) decreased daily after treatment and approached reference range values by the eighth day. PLT and haematocrit (HCT) increased daily after treatment and approached reference range values by the fourth day. WBC and haptoglobin increased after treatment and then decreased from the third and fourth days, respectively, to the eighth day. The diagnostic sensitivity of CRP, SAA and PLT was significantly higher compared to haptoglobin, ESR, HCT and the WBC count. CRP and SAA were of clinical use in monitoring the response to antibabesial treatment.
Izvorni jezik
Engleski
Znanstvena područja
Veterinarska medicina
POVEZANOST RADA
Projekti:
053-0532266-2220 - Odgovor akutne faze i aktivnost plazmatskih sustava u babeziozi (Mrljak, Vladimir, MZOS ) ( CroRIS)
Ustanove:
Veterinarski fakultet, Zagreb
Profili:
Nada Kučer
(autor)
Vladimir Mrljak
(autor)
Tatjana Živičnjak
(autor)
Željko Romić
(autor)
Ivana Kiš
(autor)
Zoran Šimec
(autor)
Vesna Matijatko
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE