Pregled bibliografske jedinice broj: 193612
Correlation between antibody epitopes and functional regions on the mouse CD8 molecule
Correlation between antibody epitopes and functional regions on the mouse CD8 molecule // Immunobiology, 189 (1993), 1-2; 12-12 (podatak o recenziji nije dostupan, kratko priopcenje, znanstveni)
CROSBI ID: 193612 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Correlation between antibody epitopes and functional
regions on the mouse CD8 molecule
Autori
Brajša, Karmen ; Eichmann, Klaus
Izvornik
Immunobiology (0171-2985) 189
(1993), 1-2;
12-12
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, kratko priopcenje, znanstveni
Ključne riječi
epitopes CD8 funcional regeions
Sažetak
CD8 is a heterodimeric membrane glycoprotein on MHC class I restricted lymphocytes that cooperates with TCR in the recognition of MHC class I molecules presenting antigenic peptides. Cooperaton has two components: enhancment of affinity of MHC/TCR interaction, and signal transduction through the T cell membrane. Using pannel of monoclonal antibodies, three to alpha chain and three to beta chain of mouse CD8, we could dfine two epitope clusters on the CD8 molecule. Epitope cluster I seems to be associated with MHC binding and apitope cluster II seems to be involved with interaction of CD8/TCR. Both clusters include epitopes on alpha and beta chain of CD8 molecule.
Izvorni jezik
Engleski
Znanstvena područja
Biologija
Citiraj ovu publikaciju:
Časopis indeksira:
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
Uključenost u ostale bibliografske baze podataka::
- Index Medicus
- PubMed
