Naslov
Wistar-Zagreb 5HT Rat: A New Animal Model of Alcoholism

Autori
Čičin-Šain, Lipa ; Bordukalo-Nikšić, Tatjana ; Jernej, Branimir

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstracts of the 2nd Croatian Conference on Alcoholism and other Addictions and 6th Alpe-Adria Conference on Alcoholism ; u: Alcoholism. Supplement 40 (2004) (S) / Thaller, Vlatko - Zagreb : Center for study and Control of Alcoholism and Addictions, Zagreb, Croatia, International Council on Alcohol and Addictions, Lausanne, and Alcohol Research Ceneter, University of Trieste, 2004, 92-93

Skup
2nd Croatian Conference on Alcoholism and other Addictions and 6th Alpe-Adria Conference on Alcoholism

Mjesto i datum
Opatija, Hrvatska, 01.10.2004. - 03.10.2004

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Wistar-Zagreb 5HT rat; serotonin; ethanol preference; alcoholism

Sažetak
Serotonin (5HT) system plays an important role in the neurobiological mechanisms underlying the regulation of alcohol intake. There is evidence that brain 5HT deficiency is associated with alcoholism, from both clinical and experimental sources. The experimental studies on the relationship between 5HT activity and alcohol consumption have often been performed on rat sub-lines, selectively bred to be extreme for ethanol intake and preference. For this study, we have used an inverse approach: comparasion of ethanol drinking pattern in rat sub-lines selectively bred for differences in the activity of 5HT system.

Izvorni jezik
Engleski

Znanstvena područja
Biologija

POVEZANOST RADA