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Pregled bibliografske jedinice broj: 187628

Synthesis and characterization of thiomers of polyaspartamide type


Bubenik Biličić, Mirela; Filipović-Grčić, Jelena; Martinac, Anita; Barbarić, Monika; Zorc, Branka; Cetina-Čižmek, Biseraka; Tudja, Petar
Synthesis and characterization of thiomers of polyaspartamide type // International journal of pharmaceutics, 291 (2005), 1-2; 211-219 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 187628 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Synthesis and characterization of thiomers of polyaspartamide type

Autori
Bubenik Biličić, Mirela ; Filipović-Grčić, Jelena ; Martinac, Anita ; Barbarić, Monika ; Zorc, Branka ; Cetina-Čižmek, Biseraka ; Tudja, Petar

Izvornik
International journal of pharmaceutics (0378-5173) 291 (2005), 1-2; 211-219

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
thiomer; polyaspartamide; thioglycolic; mucoadhesion; micoparticles

Sažetak
Synthesis of poly[alfa, beta-(N-2-hydroxyethyl-dl-aspartamide)-thioglycolic acid (PHEA-TGA)conjugate as a new polyaspartamide thiomer is described. The parent polymer PHEA is chemically modified by introducing sulphydryl-bearing compound thioglycolic acid. By varying the reaction conditions several batches of PHEA-TGA conjugates were prepared and analyzed. Tensile studies revealed that totalwork of adhesion of PHEA-TGA increased more than twice compared to the unmodified polymer. Microparticles prepared from the thiolated polymer preserved its bioadhesive properties.

Izvorni jezik
Engleski

Znanstvena područja
Farmacija



POVEZANOST RADA


Projekti:
0006561
0006543

Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb


Citiraj ovu publikaciju:

Bubenik Biličić, Mirela; Filipović-Grčić, Jelena; Martinac, Anita; Barbarić, Monika; Zorc, Branka; Cetina-Čižmek, Biseraka; Tudja, Petar
Synthesis and characterization of thiomers of polyaspartamide type // International journal of pharmaceutics, 291 (2005), 1-2; 211-219 (međunarodna recenzija, članak, znanstveni)
Bubenik Biličić, M., Filipović-Grčić, J., Martinac, A., Barbarić, M., Zorc, B., Cetina-Čižmek, B. & Tudja, P. (2005) Synthesis and characterization of thiomers of polyaspartamide type. International journal of pharmaceutics, 291 (1-2), 211-219.
@article{article, author = {Bubenik Bili\v{c}i\'{c}, Mirela and Filipovi\'{c}-Gr\v{c}i\'{c}, Jelena and Martinac, Anita and Barbari\'{c}, Monika and Zorc, Branka and Cetina-\v{C}i\v{z}mek, Biseraka and Tudja, Petar}, year = {2005}, pages = {211-219}, keywords = {thiomer, polyaspartamide, thioglycolic, mucoadhesion, micoparticles}, journal = {International journal of pharmaceutics}, volume = {291}, number = {1-2}, issn = {0378-5173}, title = {Synthesis and characterization of thiomers of polyaspartamide type}, keyword = {thiomer, polyaspartamide, thioglycolic, mucoadhesion, micoparticles} }
@article{article, author = {Bubenik Bili\v{c}i\'{c}, Mirela and Filipovi\'{c}-Gr\v{c}i\'{c}, Jelena and Martinac, Anita and Barbari\'{c}, Monika and Zorc, Branka and Cetina-\v{C}i\v{z}mek, Biseraka and Tudja, Petar}, year = {2005}, pages = {211-219}, keywords = {thiomer, polyaspartamide, thioglycolic, mucoadhesion, micoparticles}, journal = {International journal of pharmaceutics}, volume = {291}, number = {1-2}, issn = {0378-5173}, title = {Synthesis and characterization of thiomers of polyaspartamide type}, keyword = {thiomer, polyaspartamide, thioglycolic, mucoadhesion, micoparticles} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE





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