Pregled bibliografske jedinice broj: 187628
Synthesis and characterization of thiomers of polyaspartamide type
Synthesis and characterization of thiomers of polyaspartamide type // International journal of pharmaceutics, 291 (2005), 1-2; 211-219 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 187628 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Synthesis and characterization of thiomers of polyaspartamide type
Autori
Bubenik Biličić, Mirela ; Filipović-Grčić, Jelena ; Martinac, Anita ; Barbarić, Monika ; Zorc, Branka ; Cetina-Čižmek, Biseraka ; Tudja, Petar
Izvornik
International journal of pharmaceutics (0378-5173) 291
(2005), 1-2;
211-219
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
thiomer; polyaspartamide; thioglycolic; mucoadhesion; micoparticles
Sažetak
Synthesis of poly[alfa, beta-(N-2-hydroxyethyl-dl-aspartamide)-thioglycolic acid (PHEA-TGA)conjugate as a new polyaspartamide thiomer is described. The parent polymer PHEA is chemically modified by introducing sulphydryl-bearing compound thioglycolic acid. By varying the reaction conditions several batches of PHEA-TGA conjugates were prepared and analyzed. Tensile studies revealed that totalwork of adhesion of PHEA-TGA increased more than twice compared to the unmodified polymer. Microparticles prepared from the thiolated polymer preserved its bioadhesive properties.
Izvorni jezik
Engleski
Znanstvena područja
Farmacija
POVEZANOST RADA
Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb
Profili:
Branka Zorc
(autor)
Jelena Filipović-Grčić
(autor)
Monika Barbarić
(autor)
Anita Hafner
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE