Naslov
Influence of hepatectomy and Sandostatin on disaccharidase activities in mice

Autori
Varljen, Jadranka ; Milin, Čedomila ; Caser, Linda ; Eraković, Vesna ; Verbanac, Donatella ; Peršić, Mladen

Izvornik
Acta pharmaceutica (1330-0075) 44 (1994); 11-17

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
disaccharidase activity; hepatectomy; Sandostatin; mice

Sažetak
Disaccharidases are brush border enzymes of intestinal mucosa subject to the influence of many factors. Maltase, sucrase and lactase values were examined in partially hepatectomized mice, treated and untreated with Sandostatin. The disaccharidase activities were determined according to the method of Dahlquist modified by Lutkić. The observed factors of the influence on disaccharidase activity in the intestinal mucosa, hepatectomy and Sandostatin, statistically significantly change enzyme activity, depending on the localization and type of enzyme (maltase, sucrase or lactase). Sandostatin mainly causes a decrease of disaccharidase values, probably due to the direct inhibitory effect on pancreatic cholecystokinin secretion. The influence of hepatectomy is more complicated and it cannot be reduced to a common denominator.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA