Naslov
Olive and corn-oil enriched diets as modulators of mineral content in submandibular gland during liver regeneration

Autori
Milin, Čedomila ; Tota, Marin ; Domitrović, Robert ; Pantović, Radojka ; Giacometti, Jasminka ; Ćuk, Mira ; Mrakovčić-Šutić, Ines ; Jakovac, Hrvoje ; Radošević-Stašić, Biserka.

Izvornik
Croatica chemica acta (0011-1643) 78 (2005), 3; 441-446

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
submandibular gland; mineral content; corn and olive oils

Sažetak
To estimate the role of submandibular gland (SMG) in liver regeneration, in this study we estimated: 1) the tissue mineral dynamics in SMG after 1/3 partial hepatectomy (pHx) and 2) the influence of olive (OO) and corn-oil (CO) enriched diets on these events. Different nutrition of BALB/c mice lasted 3 weeks, and the minerals in SMG were determined by the microwave digestion and ICP spectrometry. The diet containing CO initially suppressed the liver regeneration (at 24h) and then, similarly as OO, increased the liver growth (at 7th day). In mice on normal food, in early phase of liver regeneration in SMG accumulated Zn++ and Ca++, and decreased the concentration of Mg++. These changes were, significantly less expressed in mice fed by CO and OO enriched diets. At the end of regeneration in control animals the concentration of Zn++, Fe++, Ca++ and Mg++ in SMG inversely correlated with the regenerating index, in contrast to CO fed group, where a positive correlation was found between Mg++ and liver growth. The data imply that trace elements and diets containing different quantities of mono-and polyunsaturated fatty acids regulate the activities of SMG, which participates in the control of liver regeneration.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Temeljne medicinske znanosti

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