Pregled bibliografske jedinice broj: 1728
Palladium(II) complexes of dialkyl alpha-anilinobenzylphosphonates. Synthesis, characterization, and cytostatic activity
Palladium(II) complexes of dialkyl alpha-anilinobenzylphosphonates. Synthesis, characterization, and cytostatic activity // Journal of inorganic biochemistry, 63 (1996), 2; 125-142 doi:10.1016/0162-0134(95)00199-9 (međunarodna recenzija, članak, znanstveni)
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Naslov
Palladium(II) complexes of dialkyl alpha-anilinobenzylphosphonates. Synthesis, characterization, and cytostatic activity
Autori
Ćurić, Manda ; Tušek-Božić, Ljerka ; Vikić-Topić, Dražen ; Scarcia, Vito ; Furlani, Ariella ; Balzarini, Jan ; De Clercq, Erick
Izvornik
Journal of inorganic biochemistry (0162-0134) 63
(1996), 2;
125-142
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
anilinobenzylphosphonates ; palladium(II) complexes ; synthesis ; spectral study ; antitumor activity
Sažetak
The new palladium(II) halide complexes with diethyl and dibutyl esters of (alpha-anilino-N-benzyl)phosphonic acid and diethyl and dibutyl esters of [alpha- (4-benzeneazoanilino)-N-benzyl]phosphonic acid have been prepared and studied. All organophosphorus ligands form dihalide complexes with monodentate N-bonded ligand through the anilinobenzyl nitrogen in (alpha-anilino-N-benzyl)phosphonate complexes and through the azo nitrogen in [alpha-(4-benzeneazoanilino)-N-benzyl]phosphonate complexes, respectively, without participation of the phosphoryl group. Azobenzene containing ligands by ortho-metallation also form binuclear organo-palladium complexes with the metal-metal chloro bridge. The complexes have been identified and characterized by elemental analysis, infrared and proton NMR, as well as by magnetic and conductometric measurements. All were tested in vitro for their cytostatic activity against KB and L1210 tumor cell lines.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
