Pregled bibliografske jedinice broj: 171046
Theoretical background and practical issues of stereological methods used in neurosciences
Theoretical background and practical issues of stereological methods used in neurosciences // First FENS/IBRO International Summer School "Development and Plasticity of the Human Cerebral Cortex"
Zagreb, Hrvatska, 2003. (pozvano predavanje, međunarodna recenzija, sažetak, ostalo)
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Naslov
Theoretical background and practical issues of stereological methods used in neurosciences
Autori
Šimić, Goran
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo
Skup
First FENS/IBRO International Summer School "Development and Plasticity of the Human Cerebral Cortex"
Mjesto i datum
Zagreb, Hrvatska, 22.09.2003. - 24.09.2003
Vrsta sudjelovanja
Pozvano predavanje
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
stereology; optical disector; optical fractionator
Sažetak
Any quantitative investigation of the human brain structural elements, e.g. determination of the total number of neurons/glial cells/synapses/receptors in a given brain region must first address the following questions: What is the best method for estimating the total number of these neural structures? What are the validity and the expected precision of the obtained data? What precision must the estimates attain with respect to the scientific question? The theorethical background of modern stereological methods which are used in neuroscientific research, such as optical and physical disector, optical fractionator and nucleator were given. The second part of the talk included practical issues and demonstrations of the above mentioned methods using the StereoInvestigator software (MicroBrightField, Williston, USA) and microscope-computer interface system.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
POVEZANOST RADA
