Naslov
Polymorphism at three STR loci on chromosome 21 (D21S1411, D21S1414, and D21S1435) in Croatia

Autori
Grubić, Zorana ; Crkvenac-Gornik, Kristina ; Štingl, Katarina ; Kerhin-Brkljačić, Vesna

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni

Izvornik
Proceedings of the 20th International ISFG Congress Progress in Forensic Genetics 10 (ICS 1261) / Doutremepuich, Christian ; Morling, Niels. - Amsterdam : Elsevier, 2004, 194-196

ISBN
0-444-51505-4

Skup
International ISFG Congress Progress in Forensic Genetics 10 (20 ; 2003)

Mjesto i datum
Arcachon, Francuska, 09.09.2003. - 13.09.2003

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
D21S1411; D21S1414; D21S1435; Croatians; Down syndrome

Sažetak
In order to increase the number of STR loci for forensic DNA analysis as well as for prenatal diagnosis of Down syndrom in the Croatian population, we have studied 3 tetranucleotide STR loci on chromosome 21 (D21S1411, D21S1414, and D21S1435). One hundred and fifty six unrelated healthy individuals were tested in this study. The results clearly demonstrated that the most polymorphic locus (20 different alleles) was D21S1414 with PIC value 0.9279, while at D21S1435 locus 7 different alleles were observed with PIC value of 0.7706. The third locus, D21S1411, also showed great polymorphism with 15 distinct alleles, PIC value 0.8920.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA