Naslov
Genetic analysis of the multiplicity reactivation of UV-inactivated lambda red phage

Autori
Petranović, Mirjana ; Zahradka, Davor ; Vlahović, Ksenija ; Petranović, Dragutin

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstracts of The First Congress of Croatian Geneticists with international participation ; u: Periodicum Biologorum 100 (1998) (S) / Vitale, Branko - Zagreb : Hrvatsko prirodoslovno društvo, 1998, 39-39

Skup
Congress of Croatian Geneticists with international participation (1 ; 1998)

Mjesto i datum
Hvar, Hrvatska, 01.06.1998. - 04.06.1998

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Sažetak
Some phages survive irradiation much better upon multiple than upon single infection, a phenomenon known as multiplicity reactivation (MR). Long ago MR of UV-inactivated lred phage in E. coli cells was shown to be a manifestation of uvrA-independent, recA-dependent recombinational DNA repair. We have recently analyzed MR of UV-inactivated lred in a number of bacterial mutants deficient in DNA recombination and/or repair. The results have shown that MR is abolished in ruvC and ssb mutants, reduced in lexA (Ind-), polA, recF, recG, ruvA, and ruvB mutants, and not affected in mutH, mutL, mutS, recB, recJ, recQ, and uvrD mutants. From the early and recent results we infer that MR is based on a type of recombinational repair acting on multiple copies of gapped DNA and that this type of repair is closely related to the RecF SbcBR pathway of recombination.

Izvorni jezik
Engleski

Znanstvena područja
Biologija

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