Naslov
IgG and Ige response in cerebrospinal fluid and aqueos humor. Part 2: A comparative study of IgE

Autori
Štambuk, Nikola ; Trbojević-Čepe, Milica ; Čurković, Tihomir ; Bradarić, Nikola ; Zekan, Ljubinka ; Šarić, Marko ; Dujmov, Ivana ; Krželj, Vjekoslav

Izvornik
Neurologia Croatica (0353-8842) 42 (1993), 3; 227-236

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
CSF ; aqueos humor ; total IgE ; numerical IgE methods ; oligoclonal IgG ; IL-4 ; albumin

Sažetak
The authors observed the samples of 84 subjects, i.e. 42 CSF and 42 aqueos humor samples with matched sera.Four different numerical methods by which the transferred and intrathecally/intraocularly synthesized fractions of IgE can be analyzed in CSF and aqueos humor, were tested in control subjects and in pathologic conditions.Oligoclonal IgG IgG, LI-4 and 2 microglobulin levels are also observed.The results obtained suggested that the measurement of IL-4 and 2 microglobulin in the mentiod body fluids might be a useful adjunct to the detection of oligoclonal IgG and numerical evaluation of IgE synthesis, in situations when the intrathecally/intraocularly immune response is observed by means of CSF or aqueos humor analysis.Some specific aspects of IL-4 and 2 microglobulin behavior in CSF, aqueos humor and serum are briefly discussed.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA