Naslov
Analysis of polychlorinated biphenyl congeners in human milk collected in Zagreb, Croatia

Autori
Zubčić, Snježana ; Krauthacker, Blanka

Izvornik
Fresenius environmental bulletin (1018-4619) 13 (2004), 4; 346-352

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Human milk; human exposure; PCB congeners

Sažetak
The method previously used for the analysis of organochlorine pesticides and total PCBs was tested to analyse the following twenty PCB congeners in human milk: PCB-28, PCB-52, PCB-60, PCB-74, PCB-77, PCB-101, PCB-105, PCB-114, PCB-118, PCB-123, PCB-126, PCB-138, PCB-153, PCB-156, PCB-157, PCB-167, PCB-169, PCB-170, PCB-180 and PCB-189.The congeners were extracted with a mixture of chloroform and methanol. The extracts were cleaned up with sulphuric acid and congeners determined by gas chromatography with electron capture detection (^63Ni). The best recoveries were obtained for PCB-153 (109%), PCB-138 (102%), PCB-180 (93%) and PCB-77 (85%). The recovery rates for PCB-28, PCB-52, PCB-60 and PCB-101 were 56-58%, and for the other congeners 60-80%. This method was considered as suitable and applied for the analysis of 28 human milk samples collected during 1998/99 from the general population in Zagreb 1.5-38 weeks after childbirth. All samples contained PCB-74, PCB-138, PCB-153 and PCB-180. The concentrations of PCB-28, PCB-52, PCB-101, PCB138, PCB-153 and PCB-180 ranged from zero to 346 microgram/kg milk fat and those of the dioxin-like congeners, PCB-77, PCB-126 and PCB-169, from 0 to 35 microgram/kg milk fat. All the other congeners were found from 0 to 82 microgram/kg milk fat.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

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