Pregled bibliografske jedinice broj: 143615
The novel ketoprofenamides - synthesis and spectroscopic characterization
The novel ketoprofenamides - synthesis and spectroscopic characterization // Croatica Chemica Acta, 76 (2003), 4; 335-341 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 143615 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
The novel ketoprofenamides - synthesis and spectroscopic characterization
Autori
Zovko, Marijana ; Zorc, Branka ; Jadrijević-Mladar Takač, Milena ; Metelko, Biserka ; Novak, Predrag
Izvornik
Croatica Chemica Acta (0011-1643) 76
(2003), 4;
335-341
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
ketoprofen; amides; synthesis; characterization
Sažetak
Synthesis of a series of new ketoprofenamides (3a-h) is described. Amide formation was achieved by aminolysis of ketoprofen benzotriazolide (2) with various amines: primary, secondary, hydroxylamine and amino acid P-alanine. The structures of synthesized compounds were characterized by means of IR, H-1 and C-13 NMR spectroscopies and elemental analysis. The synthesized compounds are potential prodrugs of a well-known NSAID ketoprofen.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
POVEZANOST RADA
Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb,
Prirodoslovno-matematički fakultet, Zagreb
Profili:
Branka Zorc
(autor)
Marijana Zovko Končić
(autor)
Milena Jadrijević-Mladar Takač
(autor)
Predrag Novak
(autor)
Biserka Metelko
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus