Naslov
Effects of peptid-M (LUPEX) on cellular findings and appoptosis in uveitis and retinopathy

Autori
Kopjar, Nevenka ; Šentija, Karmela ; Štambuk, Nikola ; Garaj-Vrhovac, Vera ; Hadžija, Mirko ; Marušić-Della Marina, Branka ; Ugrinović, Nikola ; Svoboda, Zagorka ; Karaman, Ksenija ; Štambuk, Vjera

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Uveitis Today (Excerpta Medica -International Congress Series 1158) / Ohno, Shigeaki ; Aoki, Koki ; Usui, Masahiko ; Uchio, Eiichi - Amsterdam : Elsevier, 1998, 323-324

Skup
The Fourth International Symposium on Uveitis

Mjesto i datum
Yokohama, Japan, 10.10.1997. - 14.10.1997

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
peptid-M; cytogenetic findings; apoptosis; uveitis; rethinopathy

Sažetak
The results indicate that cytogenetic tests are sensitive methods for the screening and detection of genome damages in human lymphocytes obtained from the subjects suffering from different ocular and other immune-mediated diseases. Peptid-M (met-enkephalin) induce modulation of the cell cycle, its cytostatic effects with the prevention of mutation and reduction of apoptosis (programmed cell death) suggest possible applications of this pentapeptide in different diseases which involved lymphocytes dysfunctions, chromosomal aberrations and/or abnormal PBL proliferation.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Javno zdravstvo i zdravstvena zaštita

POVEZANOST RADA