Pregled bibliografske jedinice broj: 133692
HLA class I and class II polymorphism in the population of Rijeka, Croatia
HLA class I and class II polymorphism in the population of Rijeka, Croatia // Collegium Antropologicum, 26 (2002), 1; 69-75 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 133692 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
HLA class I and class II polymorphism in the population of Rijeka, Croatia
Autori
Crnić-Martinović, Marija ; Vujaklija-Stipanović, Ksenija ; Ristić, Smiljana ; Fučak, Marina ; Kapović, Miljenko ; Weiner, Mima ; Sepčić, Juraj
Izvornik
Collegium Antropologicum (0350-6134) 26
(2002), 1;
69-75
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Haplotype frequencies; Phylogenetic trees; Gene; Antigens; Alleles
Sažetak
The aim of the study was to examine frequencies of HLA-A, -B, -DR antigens and haplotypes in population of Rijeka and to compare them with general Croatian and European populations. The subjects were 117 unrelated healthy blood donors. The antigens with the highest frequencies were: A2(27, 2%), A9(16, 3%), B5(14, 8%), B12(11, 8%), B18(11, 8%), DR5(21, 6%)and DR6(13, 8%).Comparison of HLA antigens frequencies has shown statistically significant difference in I antigen with Croatian population and in 8 antigens with European population. The HLA haplotypes with high frequencies included HLA-A2, B5(6, 84%), HLA-A2, B12(6, 84%), HLA-A2, B18(6, 84%), HLA-B12, DR2(9, 78%) and HLA-B18, DR5(6, 84%).The antigens B5 showed strongest association with DR5(6, 41% ; LD=1, 30)as in general Croatian and in some European populations. The results have shown great diversity of HLA haplotypes in Rijeka population which can be the result of admixture with neighborhood immigrating populations during the history.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti
POVEZANOST RADA
Ustanove:
Medicinski fakultet, Rijeka
Profili:
Ksenija Vujaklija-Stipanović
(autor)
Juraj Sepčić
(autor)
Marija Crnić-Martinović
(autor)
Smiljana Ristić
(autor)
Mima Weiner-Črnja
(autor)
Miljenko Kapović
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Social Science Citation Index (SSCI)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE