Naslov
Distraction osteogenesis by Ilizarov and unilateral external fixators in a canine model

Autori
Kušec, Vesna ; Jelić, Mislav ; Borovečki, Fran ; Kos, Josip ; Vukičević, Slobodan ; Koržinek, Krešimir

Izvornik
International Orthopaedics (0341-2695) 27 (2003), 1; 47-52

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
osteogenesis; fixator; canine model

Sažetak
We studied distraction osteogenesis in canine experimental model using two types of external fixators, Ilizarov (n=6) or AO unilateral (n=9) external fixator. Distraction started 1 week after surgery (2x0.5 mm/day) and lasted for 3 weeks. Specimens were harvested fromweeks 7 through 12. The outcome was assessed byX-ray, histology, histomorphology and mircoradiography. Bone regeneration as observed by X-rays was satisfactory and similar in both groups. Both endochondral ossifications and intramembranous ossification were found simultaneously in both groups. In both groups, bone formation parameters were significantly higher in the area of consolidating bone. No differences in histomorphometric parameters existed between the groups. In the study period, the bone formation was enhanced and prevailed in the distraction area. This study demonstrated the utility of the canine experimental model for the study of distraction osteogenesis.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti, Veterinarska medicina

POVEZANOST RADA