Naslov
Mitogenome information in cattle breeding and diversity management: an untapped treasure?

Autori
Curik, Ino ; Brajkovic, Vladimir ; Hršak, Dalibor ; Ristov, Strahil ; Cubric Curik, Vlatka ; Novosel, Dinko

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Book of Abstracts of 1st EAAP Regional Meeting of The European Federation of Animal Science / - , 2023, 54-54

Skup
1st EAAP Regional Meeting of The European Federation of Animal Science

Mjesto i datum
Nitra, Slovačka, 26.04.2023. - 28.04.2023

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Mitogenome ; Cattle ; Breeding traits

Sažetak
Mitochondria, whose mitochondrial DNA (~16.5 Kb) or mitogenome is passed through maternal inheritance, play a critical role in the general functional aspects of mammalian cells, and their dysfunction has been associated with various metabolic phenotypes related to bioenergy. Therefore, it is surprising that information about the mitogenome has been little used in animal breeding and diversity management. In the following, we first provide an overview of the biological aspects of mito chondrial inheritance and its implications for shaping phenotypic variation. Using cattle as an example, we will show how mitogenome information can help to i) estimate the impact on quantitative traits important for cattle production, ii) identify deleterious mutations that cause disease, iii) identify ancient introgression and upgrading, iv) estimate genetic diversity and relatedness of populations, v) screen and/or identify pedigree errors, and vi) estimate mitochondrial effectiveness and its link to productive traits. Finally, we will present some recent developments where mitogenome information has been implemented in the commercial SNP chip.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Poljoprivreda (agronomija), Interdisciplinarne biotehničke znanosti

POVEZANOST RADA