Naslov
A Case of Unilateral Otologic Symptoms as Initial Manifestations of Granulomatosis With Polyangiitis

Autori
Batinović, Franko ; Krnić Martinić, Marina ; Glavina Durdov, Merica ; Sunara, Davor

Vrsta, podvrsta
Radovi u časopisima, znanstveni

Izvornik
Journal of audiology & otology (2023)

Status rada
Online first

Ključne riječi
Granulomatosis with polyangiitis ; Facial palsy ; Hearing loss ; Otalgia

Sažetak
Granulomatosis with polyangiitis (GPA) is a chronic and systematic autoimmune condition characterized by granuloma formation and necrotizing vasculitis of small to medium-sized vessels. GPA initially presents itself as respiratory and renal symptoms. Although temporal bone involvement is not uncommon, an otologic disorder is rarely the initial symptom. We present a case of a 36-year-old man who presented with unilateral ear pain, hearing loss, and facial palsy. After a series of diagnostics and temporal bone and chest imaging, he was diagnosed with GPA with multiorgan involvement. Cyclophosphamide and methylprednisolone relieved the patient’s ear pain and partially improved his hearing, facial palsy, and overall clinical condition. Although uncommon, systemic GPA may cause initial otologic symptoms and should not be dismissed as a possible cause of an otologic disease resistant to standard therapy.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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