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Pregled bibliografske jedinice broj: 1274147

Effects of Long-Term Multimodal Psychosocial Treatment on Antipsychotic-Induced Metabolic Changes in Patients With First Episode Psychosis


(HRZZ) Rojnić Kuzman, Martina; Bosnjak Kuharic, Dina; Kekin, Ivana; Makaric, Porin; Madzarac, Zoran; Koricancic Makar, Ana; Kudlek Mikulic, Suzan; Bajic, Zarko; Bistrovic, Petra; Bonacin, Dora; Vogrinc, Zeljka
Effects of Long-Term Multimodal Psychosocial Treatment on Antipsychotic-Induced Metabolic Changes in Patients With First Episode Psychosis // Frontiers in Psychiatry, 9 (2018), 1, 5 doi:10.3389/fpsyt.2018.00488 (međunarodna recenzija, članak, znanstveni)


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Naslov
Effects of Long-Term Multimodal Psychosocial Treatment on Antipsychotic-Induced Metabolic Changes in Patients With First Episode Psychosis

Autori
Rojnić Kuzman, Martina ; Bosnjak Kuharic, Dina ; Kekin, Ivana ; Makaric, Porin ; Madzarac, Zoran ; Koricancic Makar, Ana ; Kudlek Mikulic, Suzan ; Bajic, Zarko ; Bistrovic, Petra ; Bonacin, Dora ; Vogrinc, Zeljka

Kolaboracija
HRZZ

Izvornik
Frontiers in Psychiatry (1664-0640) 9 (2018); 1, 5

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
antipsychotics, schizophrenia, first episode psychosis, metabolic abnormalities, weight gain, psychosocial intervention, day hospital

Sažetak
Background: Antipsychotic-induced weight gain and metabolic abnormalities are one of the major challenges in the treatment of psychosis, contributing to the morbidity, mortality and treatment non-adherence. Different approaches were used to counteract these side effects but showed only limited or short-term effects. This study aims to analyse the effects of a long-term multimodal treatment program for first episode psychosis on antipsychotic-induced metabolic changes. Methods: We enrolled 71 patients with first episode psychosis treated at the Zagreb University Hospital Centre from 2016 until 2018. Participants were assigned to one of the two groups: day hospital program vs. treatment as usual (TAU). Outcomes were: body weight, blood glucose, lipids and cholesterol, psychopathology and global level of functioning during the 18-months follow-up. Results: Although the TAU group gained more weight and had higher increase of blood glucose, while the day hospital group had a higher increase in total cholesterol at 18th month follow-up, after the adjustment for age, gender and baseline measures, the type of treatment was not significantly associated with any of the primary outcome measures. Patients' psychopathology measures significantly decreased and their functional level significantly increased at month 18th in both groups. Conclusion: While both types of treatment were effective in reducing psychopathology and restoring the patients' level of functioning, both were relatively ineffective in counteracting antipsychotic-induced metabolic abnormalities and antipsychotic-induced weight gain.

Izvorni jezik
Engleski



POVEZANOST RADA


Projekti:
--UIP-2014-09-1245 - Biomarkeri u shizofreniji – integracija komplementarnih prisutupa u praćenju osoba s prvom psihotičnom epizodom (BIS – LF FEP) (Rojnić Kuzman, Martina) ( CroRIS)

Poveznice na cjeloviti tekst rada:

doi www.frontiersin.org

Citiraj ovu publikaciju:

(HRZZ) Rojnić Kuzman, Martina; Bosnjak Kuharic, Dina; Kekin, Ivana; Makaric, Porin; Madzarac, Zoran; Koricancic Makar, Ana; Kudlek Mikulic, Suzan; Bajic, Zarko; Bistrovic, Petra; Bonacin, Dora; Vogrinc, Zeljka
Effects of Long-Term Multimodal Psychosocial Treatment on Antipsychotic-Induced Metabolic Changes in Patients With First Episode Psychosis // Frontiers in Psychiatry, 9 (2018), 1, 5 doi:10.3389/fpsyt.2018.00488 (međunarodna recenzija, članak, znanstveni)
(HRZZ) (HRZZ) Rojnić Kuzman, M., Bosnjak Kuharic, D., Kekin, I., Makaric, P., Madzarac, Z., Koricancic Makar, A., Kudlek Mikulic, S., Bajic, Z., Bistrovic, P., Bonacin, D. & Vogrinc, Z. (2018) Effects of Long-Term Multimodal Psychosocial Treatment on Antipsychotic-Induced Metabolic Changes in Patients With First Episode Psychosis. Frontiers in Psychiatry, 9, 1, 5 doi:10.3389/fpsyt.2018.00488.
@article{article, author = {Rojni\'{c} Kuzman, Martina and Bosnjak Kuharic, Dina and Kekin, Ivana and Makaric, Porin and Madzarac, Zoran and Koricancic Makar, Ana and Kudlek Mikulic, Suzan and Bajic, Zarko and Bistrovic, Petra and Bonacin, Dora and Vogrinc, Zeljka}, year = {2018}, pages = {5}, DOI = {10.3389/fpsyt.2018.00488}, chapter = {1}, keywords = {antipsychotics, schizophrenia, first episode psychosis, metabolic abnormalities, weight gain, psychosocial intervention, day hospital}, journal = {Frontiers in Psychiatry}, doi = {10.3389/fpsyt.2018.00488}, volume = {9}, issn = {1664-0640}, title = {Effects of Long-Term Multimodal Psychosocial Treatment on Antipsychotic-Induced Metabolic Changes in Patients With First Episode Psychosis}, keyword = {antipsychotics, schizophrenia, first episode psychosis, metabolic abnormalities, weight gain, psychosocial intervention, day hospital}, chapternumber = {1} }
@article{article, author = {Rojni\'{c} Kuzman, Martina and Bosnjak Kuharic, Dina and Kekin, Ivana and Makaric, Porin and Madzarac, Zoran and Koricancic Makar, Ana and Kudlek Mikulic, Suzan and Bajic, Zarko and Bistrovic, Petra and Bonacin, Dora and Vogrinc, Zeljka}, year = {2018}, pages = {5}, DOI = {10.3389/fpsyt.2018.00488}, chapter = {1}, keywords = {antipsychotics, schizophrenia, first episode psychosis, metabolic abnormalities, weight gain, psychosocial intervention, day hospital}, journal = {Frontiers in Psychiatry}, doi = {10.3389/fpsyt.2018.00488}, volume = {9}, issn = {1664-0640}, title = {Effects of Long-Term Multimodal Psychosocial Treatment on Antipsychotic-Induced Metabolic Changes in Patients With First Episode Psychosis}, keyword = {antipsychotics, schizophrenia, first episode psychosis, metabolic abnormalities, weight gain, psychosocial intervention, day hospital}, chapternumber = {1} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • Social Science Citation Index (SSCI)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus


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