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Pregled bibliografske jedinice broj: 1274144

INTEGRATION OF COMPLEMENTARY BIOMARKERS IN PATIENTS WITH FIRST EPISODE PSYCHOSIS: RESEARCH PROTOCOL OF A PROSPECTIVE FOLLOW UP STUDY


(HRZZ) Rojnić Kuzman, Martina; Makaric, Porin; Bosnjak Kuharic, Dina; Kekin, Ivana; Rossini Gajsak, Linda; Boban, Marina; Bozina, Nada; Bozina, Tamara; Celic Ruzic, Mirela; Darmopil, Sanja et al.
INTEGRATION OF COMPLEMENTARY BIOMARKERS IN PATIENTS WITH FIRST EPISODE PSYCHOSIS: RESEARCH PROTOCOL OF A PROSPECTIVE FOLLOW UP STUDY // Psychiatria Danubina, 31 (2019), 2; 162-171 doi:10.24869/psyd.2019.162 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1274144 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
INTEGRATION OF COMPLEMENTARY BIOMARKERS IN PATIENTS WITH FIRST EPISODE PSYCHOSIS: RESEARCH PROTOCOL OF A PROSPECTIVE FOLLOW UP STUDY

Autori
Rojnić Kuzman, Martina ; Makaric, Porin ; Bosnjak Kuharic, Dina ; Kekin, Ivana ; Rossini Gajsak, Linda ; Boban, Marina ; Bozina, Nada ; Bozina, Tamara ; Celic Ruzic, Mirela ; Darmopil, Sanja ; Filipcic, Igor ; Ganoci, Lana ; Hladnik, Ana ; Madzarac, Zoran ; Malojcic, Branko ; Mihaljevic Peles, Alma ; J. Mueller, Daniel ; Ostojic, Drazenka ; Petanjek, Zdravko ; Petrovic, Ratimir ; Vogrinc, Zeljka ; Savic, Aleksandar ; Silic, Ante ; Sagud, Marina ; Zivkovic, Maja ; Bajic, Zarko ;

Kolaboracija
HRZZ

Izvornik
Psychiatria Danubina (0353-5053) 31 (2019), 2; 162-171

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Psychiatry, biomarkers, first episode psychosis

Sažetak
In this project, we recruited a sample of 150 patients with first episode of psychosis with schizophrenia features (FEP) and 100 healthy controls. We assessed the differences between these two groups, as well as the changes between the acute phase of illness and subsequent remission among patients over 18-month longitudinal follow-up. The assessments were divided into four work packages (WP): WP1- psychopathological status, neurocognitive functioning and emotional recognition ; WP2- stress response measured by saliva cortisol during a stress paradigm ; cerebral blood perfusion in the resting state (with single photon emission computed tomography (SPECT) and during activation paradigm (with Transcranial Ultrasonography Doppler (TCD) ; WP3-post mortem analysis in histologically prepared human cortical tissue of post mortem samples of subjects with schizophrenia in the region that synaptic alteration was suggested by WP1 and WP2 ; WP4- pharmacogenetic analysis (single gene polymorphisms and genome wide association study (GWAS). We expect that the analysis of these data will identify a set of markers that differentiate healthy controls from patients with FEP, and serve as an additional diagnostic tool in the first episode of psychosis, and prediction tool which can be then used to help tailoring individualized treatment options. In this paper, we describe the project protocol including aims and methods and provide a brief description of planned post mortem studies and pharmacogenetic analysis.

Izvorni jezik
Engleski



POVEZANOST RADA


Projekti:
--UIP-2014-09-1245 - Biomarkeri u shizofreniji – integracija komplementarnih prisutupa u praćenju osoba s prvom psihotičnom epizodom (BIS – LF FEP) (Rojnić Kuzman, Martina) ( CroRIS)

Poveznice na cjeloviti tekst rada:

doi hrcak.srce.hr

Citiraj ovu publikaciju:

(HRZZ) Rojnić Kuzman, Martina; Makaric, Porin; Bosnjak Kuharic, Dina; Kekin, Ivana; Rossini Gajsak, Linda; Boban, Marina; Bozina, Nada; Bozina, Tamara; Celic Ruzic, Mirela; Darmopil, Sanja et al.
INTEGRATION OF COMPLEMENTARY BIOMARKERS IN PATIENTS WITH FIRST EPISODE PSYCHOSIS: RESEARCH PROTOCOL OF A PROSPECTIVE FOLLOW UP STUDY // Psychiatria Danubina, 31 (2019), 2; 162-171 doi:10.24869/psyd.2019.162 (međunarodna recenzija, članak, znanstveni)
(HRZZ) (HRZZ) Rojnić Kuzman, M., Makaric, P., Bosnjak Kuharic, D., Kekin, I., Rossini Gajsak, L., Boban, M., Bozina, N., Bozina, T., Celic Ruzic, M. & Darmopil, S. (2019) INTEGRATION OF COMPLEMENTARY BIOMARKERS IN PATIENTS WITH FIRST EPISODE PSYCHOSIS: RESEARCH PROTOCOL OF A PROSPECTIVE FOLLOW UP STUDY. Psychiatria Danubina, 31 (2), 162-171 doi:10.24869/psyd.2019.162.
@article{article, author = {Rojni\'{c} Kuzman, Martina and Makaric, Porin and Bosnjak Kuharic, Dina and Kekin, Ivana and Rossini Gajsak, Linda and Boban, Marina and Bozina, Nada and Bozina, Tamara and Celic Ruzic, Mirela and Darmopil, Sanja and Filipcic, Igor and Ganoci, Lana and Hladnik, Ana and Madzarac, Zoran and Malojcic, Branko and Mihaljevic Peles, Alma and J. Mueller, Daniel and Ostojic, Drazenka and Petanjek, Zdravko and Petrovic, Ratimir and Vogrinc, Zeljka and Savic, Aleksandar and Silic, Ante and Sagud, Marina and Zivkovic, Maja and Bajic, Zarko}, year = {2019}, pages = {162-171}, DOI = {10.24869/psyd.2019.162}, keywords = {Psychiatry, biomarkers, first episode psychosis}, journal = {Psychiatria Danubina}, doi = {10.24869/psyd.2019.162}, volume = {31}, number = {2}, issn = {0353-5053}, title = {INTEGRATION OF COMPLEMENTARY BIOMARKERS IN PATIENTS WITH FIRST EPISODE PSYCHOSIS: RESEARCH PROTOCOL OF A PROSPECTIVE FOLLOW UP STUDY}, keyword = {Psychiatry, biomarkers, first episode psychosis} }
@article{article, author = {Rojni\'{c} Kuzman, Martina and Makaric, Porin and Bosnjak Kuharic, Dina and Kekin, Ivana and Rossini Gajsak, Linda and Boban, Marina and Bozina, Nada and Bozina, Tamara and Celic Ruzic, Mirela and Darmopil, Sanja and Filipcic, Igor and Ganoci, Lana and Hladnik, Ana and Madzarac, Zoran and Malojcic, Branko and Mihaljevic Peles, Alma and J. Mueller, Daniel and Ostojic, Drazenka and Petanjek, Zdravko and Petrovic, Ratimir and Vogrinc, Zeljka and Savic, Aleksandar and Silic, Ante and Sagud, Marina and Zivkovic, Maja and Bajic, Zarko}, year = {2019}, pages = {162-171}, DOI = {10.24869/psyd.2019.162}, keywords = {Psychiatry, biomarkers, first episode psychosis}, journal = {Psychiatria Danubina}, doi = {10.24869/psyd.2019.162}, volume = {31}, number = {2}, issn = {0353-5053}, title = {INTEGRATION OF COMPLEMENTARY BIOMARKERS IN PATIENTS WITH FIRST EPISODE PSYCHOSIS: RESEARCH PROTOCOL OF A PROSPECTIVE FOLLOW UP STUDY}, keyword = {Psychiatry, biomarkers, first episode psychosis} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • Social Science Citation Index (SSCI)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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