Naslov
Clostridioides difficile infekcije u hospitaliziranih bolesnika liječenih od COVID-19 bolesti
(Clostridioides difficile infections in hospitalized patients treated for the COVID-19 disease)

Autori
Magaš, Morana ; Švegar, Davorka ; Barać, Nives ; Abram, Maja

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, neobjavljeni rad, znanstveni

Izvornik
11. kongres Hrvatske udruge medicinskih sestara s međunarodnim sudjelovanjem / - , 2022, 21-21

Skup
Sestrinstvo bez granica

Mjesto i datum
Opatija, Hrvatska, 09.06.2022. - 12.06.2022

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Domaća recenzija

Ključne riječi
Clostridioides difficile infekcije, COVID-19, hospitalizacija
(Clostridioides difficile infection, COVID-19, hospitalization)

Sažetak
Introduction: Clostridioides difficile was first isolated in 1935, then did not generate much interest, but in 1978. reports were published that identified its connection to pseudomembranous enterocolitis. There has been a dramatic change in the epidemiology of infections caused by CD. Consequently, the CD turned into the most common cause of diarrhoea acquired in healthcare institutions. It is known that CD appears as a complication of antibiotic treatment, but also as a causative agent of hospital infections. According to Luo and associates, CDI affects 13 in every 1, 000 patients, and in about 75% of cases, it was an infection that occurred during hospitalization. Objective: To determine the total number of CD infections, both in COVID departments and in the Central Respiratory Centre for intensive treatment of COVID patients during the pandemic caused by the SARS-CoV-2 virus in patients hospitalized due to more severe forms of COVID-19. Determine if there is an association and significance between the number of sick days and the moment of occurrence of CD infection. Methods: Retrospective research was carried out at the Clinical Hospital Center Rijeka. The research period covers two years in 2020 and 2021. Hospitalized patients with clinical imaging and positive CD isolate were included. Statistical analysis included descriptive analysis and calculation of the association between variables. Results: In 2020. of the total number of patients with CDI, 2.3% was related to patients treated in COVID wards. In 2021., this percentage was 15.9%. In 2020., of the total number of patients with CDI, 4.7% was related to patients treated at CRC. In 2021., this percentage was 3%. Of the total CD infections in Clinical Hospital Centre Rijeka in the two years observed, 13% of CDIs relate to COVID-19 patients. The average days from admission to the onset of CD infection was 14 days. The average number of hospital days was 27 days. The value of Pearson's correlation coefficient between the data set of the number of days of hospitalization and the number of days from admission to hospital treatment to patient positivity was r = +0.64. The determination coefficient is r2=0.41. Conclusion: The length of the duration of hospitalization of patients compared to the day the CD infection occurred carries a significance of 41% of the common values. Although there is a linear correlation between the incidence of CD infection and the duration of hospitalization, statistics indicate that it is not possible to claim that CD infection is a cross-infection. The incidence of CDI infection is influenced by antibiotic therapy, the clinical and immune condition of patients as well as the microbiota of patients.

Izvorni jezik
Hrvatski, engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA